Tuesday, January 25, 2011

KILAS RISET: APAKAH NUTRITIONAL MARKERS DALAM CAIRAN LUKA DAPAT MEREFLEKSIKAN STATUS PRESSURE ULCER?


Haryanto, S.Kep, Ners, MSN, ETN
Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak
Evaluasi karakteristik cairan luka untuk pengkajian pressure ulcer di klinik membutuhkan pertimbangan tenaga ahli. Shinji Izaka et al dalam studinya dengan menggunakan metode crosssectional memfokuskan untuk menginvestigasi nutritional marker pada cairan luka sebagai alat yang objektif untuk merefleksikan status pressure ulcer  berdasarkan fase penyembuhan, infeksi dan granulasi khususnya nilai serum.

Sampel yang digunakan berjumlah 28 pasien dengan 32 luka full thickness pressure ulcer. Nilai albumin, total protein, glukosa dan zinc yang didapat dari cairan luka diukur. Pada status pressure ulcer , fase penyembuhan dan infeksi dievaluasi berdasarkan tanda-tanda klinik dan derajat pembentukan jaringan granulasi ditentukan berdasarkan konsentrasi hydroxyproline.

Berdasarkan studi ini, Shinji mengatakan rasio cairan luka/serum secara signifikan lebih rendah selama fase inflammasi daripada fase proliferasi (p50.020). Cairan pada luka infeksi mengandung glukosa kurang dari (0.3–1.0 mmol/L) dari pada luka yang tidak terinfeksi (5.0–7.6 mmol/L).

Ada hubungan negative antara rasio cairan luka/serum untuk glukosa dengan nilai hydroxyproline pada fase proliferasi (r5_0.73, p50.007), kecuali nilai zinc pada cairan luka menunjukkan hubungan positif (r50.61, p50.028).

Dari hasil studi ini, Shinji mengatakan bahwa penentuan nutritional markers pada cairan luka khususnya rasio cairan luka.serum kemungkinan dapat berguna untuk mengevaluasi status lokal Pressure Ulcer.

Sumber:
Iizaka. S et al., Do nutritional markers in wound fluid reflect pressure ulcer
status? Wound Rep Reg (2010) 18: 31–37



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